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Pharmaceutical Machinery

For a long time,  Capsule filling machine, multi-use hand-capsule board, one by one will be installed must first insert a powder capsule shell hole is filled with powder and then one by one wearing cap, this method labor intensive, low efficiency, but because of hand-capsule board low price for small volume clinics, pharmacies, preparation room, the family is still appropriate. For the medium and large volume production units, some with automatic  Capsule filling machine, although the filling sets fast, but it is difficult to overcome two shortcomings: First, fully automatic machine-to-capsule shell size requirements were very strict, can not be applied Ordinary molded capsule shell.
 
Ordinary molded capsule shell diameter, length measurements are quite different for the fully automatic machine, prone to an empty hole, leaking powder, deformation, and even card machines; such as pre-screening capsule shell, the capsule shell utilization greatly reduced, as well as Although some units expensive price for a fully automatic machine, later forced to have to retain the original production. The second is expensive. Automatic machine at least 10 million yuan each, or even as high as 20 million, and the maintenance costs of large, accessories demanding. Therefore, many small and medium units can only watch the machines disappointed, prohibitive. Our factory successfully resolved this problem. JCT-type Capsule filling machine , fully automatic machine has absorbed the advantages and minimize the number of complex organizations, but the effect is not obvious to the cost of a larger place, changed manually. This price is only fully automatic machine, one of 10-20 minutes, more importantly, the filling speed, size, large differences in the ordinary molded capsule shell can be fully utilized. The machine will be installed capsule shell finishing powder, capsule cap order, capsule set into one, compact and convenient. This machine is suitable for both small and medium sized pharmaceutical companies, health care products factory, hospital, clinics, small in volume, such as 2-3 units used simultaneously, but also suitable for mass production.
 
This machine is the country's first, has applied for patents, in the provinces without proxy, please user's attention. Steps:
1, press the "power switch" in the green button, power supply connected.
2, the slow adjustment "Vibration intensity adjustment knob" clockwise rotation, this time with the "vibration bracket" United as one of the finishing plate begin to vibrate in his hand to touch finishing plate, adjusted to the feel of a certain oscillation intensity.
3, to be installed into the shell powder capsules "filled powder capsule shell finishing disk" inside, each with approximately 300 or so. Capsule cap will be placed in "capsule cap finishing disk" in each of about 300 or so. Finishing disc with plexiglass plate production. Above, there are many large drilling under the small funnel-shaped hole, hole diameter and capsule number of compatible diameter.
4, about 30 seconds, loading powder capsules and capsule caps that fall into the hole, the opening facing up. In case of the individual openings down, the used capsule caps gently downward pressure sets, you can easily set up.
5, the level of hand-held equipment powder capsule shell access plate (the end of the diagram drawn, has random ready, then board a round hole), in order to live where the lower plate a push gently, sort of fitted intraday powder capsule shell on the will fall into the next down the hole in the plate, remove the access panels, the same method, with the capsule cap then remove the capsule cap sheet.
6, can be prepared at the end of an area of 500500mm2, four sides of the powder height of about 10mm square plate, built-in powder, capsule shell powder will be installed next board flat on the powder side disk. The random distribution of the plexiglass box cover at the loaded powder capsule then board shovel bucket with a handful of powder into the box, with a scraping edge frame, you can filled with powder, and scraped off the excess powder.
7, with the random distribution of the capsule cap set board (the end of the diagram drawn, set the board has round hole), on the capsule cap access panel, there is alignment hole, it is easy to place. Flip capsule cap access plate so that the capsule opening down, the sets have been installed in a good powder for loading powder capsule shell access on-board, but also alignment hole, it is easy to set together.
8, it will be nested into the capsule plate "capsule wearing a cap molding board" following the cavity, hands down flip, "Strut" and in place, no need to beware of excessive force because there are positioned under the control of pressure. Remove the nested capsules plate, capsules can be poured.
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ALU-PVC Blister packing machine

ALU-PVC Blister packing machine is the latest packaging machine for tablet, bolus, capsule, etc. This ALU-PVC Blister Packaging Machine is widely used in pharmaceutical, food, cosmetic industry. This ALU-PVC Blister packing machine fits for aluminum and plastic compound sealing.

FEATURES

*The distance of cavity forming, hot sealing, punch/cut can be adjusted, so as to fit for different size of blister board.
*The PVC strap is dragged by grippers, the travel range is freely adjustable, and at same time it is accurate and stable.
*The reducer is low noise and long life.
*Variable speed regulation by frequency invertor.
*It is easy and precise to change over different molds.
*Optional functions are available:

1. Eye-mark, to automatically correct dragging distance of PVC strap.
2. Synchronous color tape print batch number.
3. Camera inspection and fault rejection system.

TECH SPECS

 

S/N

ITEM

PARAMETERS

1

Speed of punch/cut station

15~35 per min.

2

Max. area of cavity forming

110 x 240 mm

3

Max. range of travel

60~120 mm

4

Standard blister board Size

80 x 57 mm

(or design as per user’s request)

5

Cavity quantity per board

common capsule: 10 pcs(#0,#1), 12 pcs(#2,#3)

common tablet: 8~30 pcs

other shapes: depends on blister board design

6

Packaging material

Hard PVC: 0.20~0.50 (thickness) x 250 (width) mm

Alu. Foil: 0.02~0.17 (thickness) x 250 (width) mm

7

Power of each heating stations

Upper heat forming board: 1.5 KW

Lower heat forming board: 1.5 KW

Hot sealing station: 1.5 KW

8

Voltage/power of main elec. motor

220V 50Hz/1.5 KW

9

Compres. air for cylinder (to be prepared by user)

Qty: >0.1 m3 per min.

Pressure: 0.6~0.8 MPa

10

Chiller for molds

Water cooling, the qty of circulated water about 60 Ltrs per hr

11

Overall dimension

Length  3000 mm

Width 950 mm

Height 1600 mm

12

Total Weight

~1000 kg

 

from:china-pharmaceutical-machine

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Auto Blister Packing Machine is widely used for capsule, tablet

A & M Technology Co. Ltd.., a customer-oriented company, is committed to offer high quality machineries and services to achieve utmost customer satisfaction. main products are:Labeling Machine,Aerosol Filling Machine ,Capsule Filler,blister packaging machine ,fluid bed dryer,rotary tablet press,Pharmaceutical Machinery and so on. highly qualified and experienced team of design engineers and technicians are responsible for providing ideal solution, tailored to suit customer’s need. They aim to be more than just a supplier. and seek to be a partner of their clients.

This Auto Blister Packing Machine is widely used for capsule, tablet, etc. in pharmaceutical industry, medical apparatus, electron or hardware industry as all kinds of shapes of ALU-ALU, ALU-plastic, paper-plasatic combined sealing packing.

CHARACTERISTIC

* The electric appliance of this machine adopts PLC to control, temperature module, touch panel to operate, ease of cleaning, can be equipped with cursor device etc as customer require.
* Machine-tool track type of casting machine-base, taken these processing like backfire, maturing, high benchmark and without distortion.
* Each box of section processed through professional equipment, to assure high precision and good interchangeability.
* Forming, sealing, slitting etc. parts are all could be adjust freely on the track with triangle string and flat string, strong applicability. Small overall size, save installation space.
* Reducer adopt parallel-axes bevel wheel (with mould as a unit) to avoid loosen and smooth between chain or strap when it is driving.
* Stroke can be adjust freely, widely used, easy of operation, stable running.
* Mould located by male pin, ease and accuracy of changing mould. Product any size and shapes of strip by changing the mould on the machine, and it can also pack for liquid if liquid filling device equipped.
* It adopts up & down net pattern concavo-convex to conjugate, multi-step air cylinder, double-heat sealing, quality sealing.

from:china-pharmaceutical-machine

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Auto Aerosol Filling Machine Line consists

The bottle automatically pressurizes and liquefies propellant. At proper pressure level, the liquid propellant is loaded by fixed volume. The propellant could be propane, butane, freon, dimethyether, carbon dioxide, nitrogen, oxygen, compressed air and 134a, etc.

Technical Data

Filling volume: 30-500 ML
Filling tolerance: +/-1%
Bottle height: 70-330mm
Production Capacity: 800-1200 bottles/hour


Auto Aerosol Filling Machine Line consists of an CAN FEEDING MACHINE, CONVEYORS, INDEXED LIQUID FILLER, VACUUM EXTRACTOR, INDEXED VALVE SEALER AND PROPELLANT FILLER, and can automatically execute procedures as Aerosol Filling Machine can conveying, blowing, liquid filling, vacuum extraction, valve pressing, capping and propellant filling.


SPECIFCATION FOR LIQUID FILLING STATION

Single-head filling capacity

10-250 ml

Overall filling capacity

10-750 ml

Repetitive filling accuracy

≤±1%

Applicable can

Height

85-315 mm

Diameter

Φ35

Φ52

Φ65

Working pressure

0.4-0.6 MPa

Max air consumption

1.0 m3/min

Production capacity

30-40 cpm


SPECIFICATION FOR SEALING & PROPELLANT FILLING STATION

Single-head filling capacity (ml)

10-250 ml

Overall filling capacity (ml)

10-750 ml

Repetitive filling accuracy

≤±1%

Applicable can

Height

85-315 mm

Diameter

Φ35

φ52

φ65

Work pressure

0.4-0.7 MPa

Max. Air consumption

1.0 m3/min

Production capacity

30-40 cpm

 from:china-pharmaceutical-machine

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The working principle of dryer

The traditional dryer works: Traditional clothes dryer will heat the surrounding ambient air, transported to the surrounding drum. The resulting hot and humid air is excluded, leaving the dry air to continue drying process. Traditional design there is no recovery of heat, so it is very inefficient. However, the traditional design is simple, reliable and inexpensive.
 
Vapor Compression dryer: This is a newly developed dryer, dryer than the traditional more advanced. It works not by hot air to dry clothes. First, the clothes drum heated to 100 ° C, the resulting water vapor hot and humid. Drum vapor escape after being collected and compressed. Under the influence of pressure, water vapor liquefaction and release heat, and then sent back to roller generated heat, so that heat can be achieved recycling. With this technology, drying machine, its efficiency can reach twice the conventional dryer, drying time can be shortened to a half of a traditional dryer.
 
 

The Hot Air Drying Oven is used for drying glass bottles, rubber stoppers, aluminum caps in pharmaceutical industry. HEPA filters inside oven, air supply inlet/outlet, which conforms to GMP.

HOT AIR DRYING OVEN FEATURES

* HMI and PLC, precisely control the process parameter
* Record print, failure alarm etc functions
* Complete 100-class laminar flow purification system
* Air circulation air is adjustable to ensure the temperature uniformity inside oven
* Mechanical inter-lock door
* We can change to water cooling according to user's requirement
* There are several temperature test points inside oven, for GMP validation

 From: china-pharmaceutical-machine
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Capsule Filling Machine Main technical parameters

Capsule Filling Machine filling speed, size difference is small, the machine will be installed capsule shell finishing powder, capsule cap order, capsule set into one, compact and convenient. Is suitable for small and medium sized pharmaceutical companies, health care products factory, hospital, clinics, small in volume, such as 2-3 units used simultaneously, but also suitable for mass production.

 
Capsule Filling Machine Main technical parameters:
application of capsules:0 # - 4 #
capacity: 20000 / h
Supply voltage: 220V 50Hz 300W
Size: 1000X500X950
Machine Weight: 100kg
 
1, press the "Power switch "in the green button, power supply connected.
2, the slow adjustment "Vibration intensity adjustment knob" clockwise rotation, this time with the "vibration bracket" United as one of the finishing plate began to vibration, hand-to-order plates, adjusted to the feel of a certain oscillation intensity.
3, to be installed into the shell powder capsules "filled powder capsule shell finishing disk" inside, each with approximately 300 or so. Capsule cap will be placed in "capsule cap finishing disk" in each of about 300 or so. Finishing disc with plexiglass plate production, drilling above there are many large hole under the small funnel-shaped, hole diameter and capsule diameter of the corresponding numbers.
4, about 30 seconds, loading powder capsule shell and capsule caps that fall into the hole, the opening facing up. In case of the individual openings down, the capsule can be gently pressed down cap sleeve, you can set up.
5, the level of hand-held equipment powder capsule shell access plate (the end of the diagram drawn, has random ready, then board a round hole), in order plate gently look inside the lower part of a push, finishing the installation disk shell powder capsules on the will fall into the next down the hole in the plate, then remove the access panel. The same method, with the capsule cap then remove the capsule cap sheet.
6, can be prepared at the end of an area of 500 × 500mm2, four sides of the powder height of about 10mm square plate, built-in powder, capsule shell powder will be installed next board flat on the powder side disk. And then randomly assigned plexiglass box cover at the loaded powder capsule then board shovel bucket with a handful of powder into the box, with a scraping edge frame, you can filled with powder, and scraped off the excess powder.
7, with the random distribution of the capsule cap set board (the end of the diagram drawn, set the board has round hole), on the capsule cap access panel, there is alignment hole, it is easy to place. Flip capsule cap access plate so that the capsule opening down, the sets have been installed in a good powder for loading powder capsule shell access on-board, but also alignment hole, it is easy to set together.
8, it will be nested into the capsule plate "capsule wearing a cap molding board" following the cavity, hands down flip, "Strut" and in place, no need to beware of excessive force because there are positioned under the control of pressure high. Remove the nested capsules plate, capsules can be poured.
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Auto Blister Packaging Machine PDPBO-250(320)H

This blister packaging machine is widely used for capsule, tablet, etc. in pharmaceutical industry, medical apparatus, electron or hardware industry as all kinds of shapes of ALU-ALU, ALU-plastic, paper-plasatic combined sealing packing.

CHARACTERISTIC


* The electric appliance of this machine adopts PLC to control, temperature module, touch panel to operate, ease of cleaning, can be equipped with cursor device etc as customer require.
* Machine-tool track type of casting machine-base, taken these processing like backfire, maturing, high benchmark and without distortion.
* Each box of section processed through professional equipment, to assure high precision and good interchangeability.
* Forming, sealing, slitting etc. parts are all could be adjust freely on the track with triangle string and flat string, strong applicability. Small overall size, save installation space.
* Reducer adopt parallel-axes bevel wheel (with mould as a unit) to avoid loosen and smooth between chain or strap when it is driving.
* Stroke can be adjust freely, widely used, easy of operation, stable running.
* Mould located by male pin, ease and accuracy of changing mould. Product any size and shapes of strip by changing the mould on the machine, and it can also pack for liquid if liquid filling device equipped.
* It adopts up & down net pattern concavo-convex to conjugate, multi-step air cylinder, double-heat sealing, quality sealing.Auto Blister Packaging Machine      PDPBO-250(320)H

From: http://www.blogigo.com/XianfengProducts

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See the characteristic ,when buy a blister packing machine

This Auto Blister Packaging Machine is widely used for capsule, tablet, etc. in pharmaceutical industry, medical apparatus, electron or hardware industry as all kinds of shapes of ALU-ALU, ALU-plastic, paper-plasatic combined sealing packing.

CHARACTERISTIC


* The electric appliance of this Blister Packaging Machine adopts PLC to control, temperature module, touch panel to operate, ease of cleaning, can be equipped with cursor device etc as customer require.
* Machine-tool track type of casting machine-base, taken these processing like backfire, maturing, high benchmark and without distortion.
* Each box of section processed through professional equipment, to assure high precision and good interchangeability.
* Forming, sealing, slitting etc. parts are all could be adjust freely on the track with triangle string and flat string, strong applicability. Small overall size, save installation space.
* Reducer adopt parallel-axes bevel wheel (with mould as a unit) to avoid loosen and smooth between chain or strap when it is driving.
* Stroke can be adjust freely, widely used, easy of operation, stable running.
* Mould located by male pin, ease and accuracy of changing mould. Product any size and shapes of strip by changing the mould on the machine, and it can also pack for liquid if liquid filling device equipped.
* It adopts up & down net pattern concavo-convex to conjugate, multi-step air cylinder, double-heat sealing, quality sealing.


Primary Competitive Advantages :

   1. Well and High Quality Control
   2. Prompt Delivery
   3. New Product
   4. Customer's Designs and Logos are Welcome
   5. In a Variety of Designs
   6. ODM Accepted
   7. OEM Accepted

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High Quality Capsule filling machine

This paper  presents a cost-effective method for fast and accurate in-line weighing of hard gelatin capsules based on the optimized capacitance sensor and real-time processing of the capsule capacitance profile resulting from 5000 capacitance measurements per second. First, the effect of the shape and size of the capacitive sensor on the sensitivity and stability of the measurements was investigated in order to optimize the performance of the system. The method was tested on two types of hard gelatin capsules weighing from 50 mg to 650 mg. The results showed that the capacitance profile was exceptionally well correlated with the capsule weight with the correlation coefficient exceeding 0.999. The mean precision of the measurements was in the range from 1 mg to 3 mg, depending on the size of the capsule and was significantly lower than the 5% weight tolerances usually used by the pharmaceutical industry.

Therefore, the method was found feasible for weighing pharmaceutical hard gelatin capsules as long as certain conditions are met regarding the Capsule filling machine and environment stability. The proposed measurement system can be calibrated by using only two or three sets of capsules with known weight. However, for most applications it is sufficient to use only empty and nominally filled capsules for calibration. Finally, a practical application of the proposed method showed that a single system is capable of weighing around 75 000 capsules per hour, while using multiple systems could easily increase the inspection rate to meet almost any requirements.


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Capsule filling machine

Capsule Filling Machine is suitable for filling human medicines and chemicals (powder, pellet, granule, pill), also Capsule Filling Machine can be used to fill vitamin, foodstuff and veterinary drugs, etc.

CHARACTERISTIC

* Touch screen, PLC program control.
* Capsule vacuum positioned mechanism to make the capsule qualified rate over 99%.
* Removable powder hopper for cleaning and easy
* Easy speed selection and closed capsule length adjustment.
* Electric appliance control system approved to CE, and international standard.
* Quick and accurate change part setup, easy to remove rotary table and ring carrier assembly.
* Fully enclosed dosing stations and rotating table for integration of the whole capsule filling plants.
* Large cam mechanism keeps the rotating table of mould together with the whole equipment running with balance, and completely guarantees the machine operating with highest precision and accuracy.

TECHNICAL PARAMETER


* Capacity 2000 per min
* Number of dosing 18
* Suitable for Capsule 00#, 0#, 1#, 2#, 3#, 4#
* Total Power 8Kw
* Overall Weight 1000Kg
* Outer Dimension 1100mm(L) x 1300mm(W) x 1800mm(H)
* Filling Tolerance + 1% Depending upon the consistency, uniformity & bulk density of powder under the controlled level of humidity.

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Auto Sticker Labeling Machine

This Auto Sticker Labeling Machine is suitable for pasting adhesive label on round bottle or container. It is widely used in pharmaceutical and food industry.

CHARACTERISTIC

* Micro computer control, parameter can be set through HMI, easy to operate
* Multiple elec. motor drive, regulate separately, reliable locating, high sensitivity
* Speed: 80-200 per min ( depends on label/bottle size)
* Bottle diameter: 30-100mm
* Voltage/Power: 220V 50Hz, 300W
* Dimension: 1600x700x1400mm
* Weight: 200kg
* Feeding direction: from left to right (or from right to left)
* Printing station is optional

**We can make according to client's request

There is a Auto Sticker Labeling Machine photo:

Auto Sticker Labeling Machine


Reference from:Pioneers International Trading Ltd. sticker labeling machine

(http://www.china-pharmaceutical-machine.com/product/47-auto-sticker-labeling-machine-pdltb-a-3cde/)

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Fluid bed dryer

Fluid bed dryer is the machine with technology combination of spray fogging and fluidizing. Fliud bed equipment utilizes high speed hot air flow to make the powder suspended and fluidized and then change it to porous granules by spraying binding solution onto it.

While the fluidized bed is formed when a quantity of a solid particulate substance (usually present in a holding vessel) is placed under appropriate conditions to cause the solid/fluid mixture to behave as a fluid. This is usually achieved by the introduction of pressurized fluid through the particulate medium.It results in the medium then having many properties and characteristics of normal fluids;

As a reliable fluid bed dryer manufacturer, the technology of Pioneers addresses the current shortfalls of fluid bed technology such as the difficulty in scaling up the process and the need to have special configurations and extra product containers depending on whether the machine is to be used as a dryer, granulator or coater.




From:http://www.china-pharmaceutical-machine.com/news/index.html

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Aerosol Machine

Aerosol Machine is one kind of our main Liquid Pharmaceutical Machinery.Pioneers has developed Semi-auto Aerosol Filler-The machine is suitable for all kinds of liquid solutions.
Semi-auto Aerosol Can Sealer,which is used for sealing various tinplate or alu valves on to cans.

 Semi-auto Aerosol Propellant Filler
The bottle automatically pressurizes and liquefies propellant. At proper pressure level, the liquid propellant is loaded by fixed volume. The propellant could be propane, butane, freon, dimethyether, carbon dioxide, nitrogen, oxygen, compressed air and 134a, etc.
Auto Aerosol Production Line
The line consists of an CAN FEEDING MACHINE, CONVEYORS, INDEXED LIQUID FILLER, VACUUM EXTRACTOR, INDEXED VALVE SEALER AND PROPELLANT FILLER.

The aerosol filling machine of Pioneers has avoided the normal problem of chinese Pharmaceutical Machine:
1.low level copy and similar low quality
2.short durability,without corollary equipment and good EffectLookSet.ini.
3.no characteristic products and solving solutions


From: http://www.china-pharmaceutical-machine.com/news/index.html

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High Containment Tablet Press

The development of tablet presses with clean-in-place (CIP) features in the mid 1990's was one of the first steps on the road to producing a truly contained solid dosage production system.

Pioneers, a company at the forefront of solid dosage technology, has been developing systems with CIP capabilities for some time and has recently taken the design of such systems even farther with the addition of technologies to ensure complete containment when processing compounds with highly active substances.We also develop the tablet machine :PGZPA-Y which avoid powder leakage and flying effectively has new powder scraper and suction device .The Rotary Tablet Press is easy to disassemble and maintain.


With the development of Tablet Coating Machine,and of Auto capsule filling machines, Pioneers was one of first suppliers of solid dosage equipment to produce machines with CIP capability. As the turret of the tablet press is interchangeable- you can produce large/small tablet in the same machine using different turret. This not only saves cleaning time and improves efficiency, but lowers equipment cost and save workshop room. It is suitable for the user making multiple tablets. From the very beginning CIP machines were particularly suitable for containment applications.



From:http://www.sbkj.com/news/index.html

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Mixing Granulator

The Mixing Granulator PGHLA is used to produce granules for tablet pressing, capsule, food, or other chemical product. This machine is suitable for pharmaceutical, chemical and food industries for granulation and drying. 
 The mixer granulator works more than the function of granulator and mixer,the Mixing and granulating are finished in one step, save time and improve efficiency.

After timing setup, the whole granulating cycle can be done automatically.Agitating elec. motor is variable speed.Use conical pan and agitator/shearing blade of special shape, to ensure uniform granules.Vacuum feeding device available as option.
The container is made of stainless steel, a GMP design.Automatic cleaning system, convenient and rapid
Safety interlock, if the container cap opens during running, the power is cut off automatically.

On the basis of customer orientation, Pioneers highly respects the use experience and experience resources of clients from more than 70 countries.  Pioneers provides customized products and a case-by-case personalized service model approved by worldwide customers.

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